General Information
SPKB ID SPKB02730
Signal sequence MQVSTAALAVLLCTMALCNQFSA
Length 23
Organism Homo sapiens (Human)
UniProt ID P10147,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02730.cif
Physicochemical Information
Molecular weight 2386.88324
Aliphatic index 114.7826087
Isoelectric point 5.826007312
Charge (pH=7) -0.125965132
Topological polar surface area 913.71
Aromaticity 0.043478261
Average rotatable bonds 3.347826087
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 35
X logP energy -9.5791
Hydropathy
Literature Information
Title BB-10010: an active variant of human macrophage inflammatory protein-1 alpha with improved pharmaceutical properties.
DOI NA,
Publication Year 1995
PubMed ID 8541527,
Patent ID NA,