SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02726

Signal sequence   MVFVRRPWPALTTVLLALLVCLGALVDA

Length  28

Organism  Homo sapiens (Human)

UniProt ID  P10082,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02726.cif

Structure  SPKB02726.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3038.78954

Aliphatic index  163.5714286

Isoelectric point  8.54983383

Charge (pH=7)   0.936449445

Topological polar surface area  1048.79

Aromaticity  0.071428571

Average rotatable bonds  3.285714286

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  36

X logP energy  -2.77356

Hydropathy 



Literature Information


Title  A new molecular form of PYY: structural characterization of human PYY(3-36) and PYY(1-36).

DOI  10.1016/0196-9781(89)90116-2,

Publication Year  1989

PubMed ID  2587421,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.