SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02724

Signal sequence   MKCIALFLVLSMVVLMAEPGEA

Length  22

Organism  Pterois volitans (Red lionfish) (Gasterosteus volitans)

UniProt ID  P0DUJ5,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02724.cif

Structure  SPKB02724.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2365.99154

Aliphatic index  141.8181818

Isoelectric point  4.258107901

Charge (pH=7)   -1.060735205

Topological polar surface area  786.48

Aromaticity  0.045454545

Average rotatable bonds  3.545454545

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  31

X logP energy  -1.7424

Hydropathy 



Literature Information


Title  Identification of a moronecidin-like antimicrobial peptide in the venomous fish Pterois volitans: Functional and structural study of pteroicidin-alpha.

DOI  10.1016/j.fsi.2017.11.003,

Publication Year  2018

PubMed ID  29108968,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.