SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02721

Signal sequence   MEMFQGLLLLLLLSMGGTWA

Length  20

Organism  Homo sapiens (Human)

UniProt ID  P0DN86,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7FIG,

Predicted Structure ID  SPKB02721.cif

Structure  SPKB02721.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2224.76264

Aliphatic index  141.5

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  752.86

Aromaticity  0.1

Average rotatable bonds  3.7

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  -1.4243

Hydropathy 



Literature Information


Title  The amino acid sequence of human chorionic gonadotropin. The alpha subunit and beta subunit.

DOI  NA,

Publication Year  1975

PubMed ID  1150658,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.