SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02720

Signal sequence   MAAGSRTSLLLAFALLCLPWLQEAGA

Length  26

Organism  Homo sapiens (Human)

UniProt ID  P0DML3,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02720.cif

Structure  SPKB02720.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2704.24074

Aliphatic index  128.0769231

Isoelectric point  6.232433001

Charge (pH=7)   -0.062218605

Topological polar surface area  1000.8

Aromaticity  0.076923077

Average rotatable bonds  3.269230769

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  35

X logP energy  -6.86203

Hydropathy 



Literature Information


Title  Amino acid sequence of human chorionic somatomammotropin.

DOI  10.1016/s0003-9861(73)80012-8,

Publication Year  1973

PubMed ID  4712450,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.