General Information
SPKB ID SPKB02716
Signal sequence MKTLLLTLLVVTIVCLDLGYS
Length 21
Organism Dendroaspis polylepis polylepis (Black mamba)
UniProt ID P0DKR6,
Motif 1..21
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02716.cif
Physicochemical Information
Molecular weight 2308.90374
Aliphatic index 190
Isoelectric point 6.157533513
Charge (pH=7) -0.06468938
Topological polar surface area 809.79
Aromaticity 0.047619048
Average rotatable bonds 3.619047619
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 31
X logP energy -2.5679
Hydropathy
Literature Information
Title Black mamba venom peptides target acid-sensing ion channels to abolish pain.
DOI 10.1038/nature11494,
Publication Year 2012
PubMed ID 23034652,
Patent ID NA,