SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02713

Signal sequence   MKLLTGLVFCSLVLSVSS

Length  18

Organism  Homo sapiens (Human)

UniProt ID  P0DJI9,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02713.cif

Structure  SPKB02713.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1897.36194

Aliphatic index  156.6666667

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  685.19

Aromaticity  0.055555556

Average rotatable bonds  3.5

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -5.1256

Hydropathy 



Literature Information


Title  Identification of two novel amyloid A protein subsets coexisting in an individual patient of AA-amyloidosis.

DOI  10.1016/0925-4439(92)90068-x,

Publication Year  1992

PubMed ID  1463770,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.