General Information
SPKB ID SPKB02712
Signal sequence MKLLTGLVFCSLVLGVSS
Length 18
Organism Homo sapiens (Human)
UniProt ID P0DJI8,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02712.cif
Physicochemical Information
Molecular weight 1867.33564
Aliphatic index 156.6666667
Isoelectric point 8.545189979
Charge (pH=7) 0.93571455
Topological polar surface area 664.96
Aromaticity 0.055555556
Average rotatable bonds 3.444444444
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 26
X logP energy -4.4865
Hydropathy 
Literature Information
Title The major proteins of human and monkey amyloid substance: Common properties including unusual N-terminal amino acid sequences.
DOI 10.1016/0014-5793(71)80506-9,
Publication Year 1971
PubMed ID 11946204,
Patent ID NA,
