SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02711

Signal sequence   MKWLLLLGLVALSEC

Length  15

Organism  Homo sapiens (Human)

UniProt ID  P0DJD7,

Motif  1..15



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02711.cif

Structure  SPKB02711.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1689.14734

Aliphatic index  182

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  570.06

Aromaticity  0.066666667

Average rotatable bonds  3.733333333

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  21

X logP energy  0.1624

Hydropathy 



Literature Information


Title  A comparative study on the NH2-terminal amino acid sequences and some other properties of six isozymic forms of human pepsinogens and pepsins.

DOI  10.1093/oxfordjournals.jbchem.a122952,

Publication Year  1989

PubMed ID  2515193,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.