SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02707

Signal sequence   MNVFFTFSLLFLAALGSC

Length  18

Organism  Bothrops atrox (Barba amarilla) (Fer-de-lance)

UniProt ID  P0CC17,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02707.cif

Structure  SPKB02707.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1981.39804

Aliphatic index  113.8888889

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  661.8

Aromaticity  0.222222222

Average rotatable bonds  3.388888889

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -2.954

Hydropathy 



Literature Information


Title  Evidence of caspase-mediated apoptosis induced by l-amino acid oxidase isolated from Bothrops atrox snake venom.

DOI  10.1016/j.cbpa.2008.07.007,

Publication Year  2008

PubMed ID  18804547,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.