SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02706

Signal sequence   MRFLIGALLTLQTLVQA

Length  17

Organism  Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus)

UniProt ID  P0CB51,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02706.cif

Structure  SPKB02706.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1888.34204

Aliphatic index  166.4705882

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  717.46

Aromaticity  0.058823529

Average rotatable bonds  3.705882353

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  24

X logP energy  -3.68943

Hydropathy 



Literature Information


Title  Amino-terminal sequence analysis of the Coccidioides immitis chitinase/immunodiffusion-complement fixation protein.

DOI  10.1128/iai.61.7.3090-3092.1993,

Publication Year  1993

PubMed ID  8514419,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.