SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02702

Signal sequence   MTFKACIAIITALCAMQVIC

Length  20

Organism  Rhipicephalus sanguineus (Brown dog tick) (Ixodes sanguineus)

UniProt ID  P0C8E7,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02702.cif

Structure  SPKB02702.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2144.75324

Aliphatic index  132

Isoelectric point  8.045790785

Charge (pH=7)   0.811765118

Topological polar surface area  725.79

Aromaticity  0.05

Average rotatable bonds  3.5

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  -3.73

Hydropathy 



Literature Information


Title  Molecular cloning and characterization of a highly selective chemokine-binding protein from the tick Rhipicephalus sanguineus.

DOI  10.1074/jbc.M704706200,

Publication Year  2007

PubMed ID  17640866,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.