SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02701

Signal sequence   RVRKKDYFGIWSFPLIIAAVCAQ

Length  23

Organism  Bos taurus (Bovine)

UniProt ID  P0C2W5,

Motif  <1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02701.cif

Structure  SPKB02701.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2682.22494

Aliphatic index  106.0869565

Isoelectric point  10.25201275

Charge (pH=7)   2.935008963

Topological polar surface area  1007.21

Aromaticity  0.173913043

Average rotatable bonds  3.695652174

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  33

X logP energy  -4.63786

Hydropathy 



Literature Information


Title  Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog.

DOI  10.1523/JNEUROSCI.3467-06.2006,

Publication Year  2006

PubMed ID  17093081,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.