SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02700

Signal sequence   MTDVSRKIRAWGRRLMIGTAAAVVLPGLVGLAGGAATAGA

Length  40

Organism  Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)

UniProt ID  P0C2T2,

Motif  1..40



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02700.cif

Structure  SPKB02700.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3936.69584

Aliphatic index  110

Isoelectric point  12.50839025

Charge (pH=7)   3.998122504

Topological polar surface area  1597.06

Aromaticity  0.025

Average rotatable bonds  3.2

Number of hydrogen bond donors  59

Number of hydrogen bond acceptors  53

X logP energy  -16.66712

Hydropathy 



Literature Information


Title  Cloning and expression of the Mycobacterium bovis BCG gene for extracellular alpha antigen.

DOI  10.1128/jb.170.9.3847-3854.1988,

Publication Year  1988

PubMed ID  2842287,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.