SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02699

Signal sequence   MVKSRKISILLAVAMLVSIMIPTTAFA

Length  27

Organism  Acetivibrio thermocellus (Hungateiclostridium thermocellum) (Clostridium thermocellum)

UniProt ID  P0C2S5,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1L1Y,

Predicted Structure ID  SPKB02699.cif

Structure  SPKB02699.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2905.69564

Aliphatic index  148.1481481

Isoelectric point  11.82305527

Charge (pH=7)   2.99739092

Topological polar surface area  1026.22

Aromaticity  0.037037037

Average rotatable bonds  3.592592593

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  39

X logP energy  -5.35863

Hydropathy 



Literature Information


Title  Dissociation of the cellulosome of Clostridium thermocellum in the presence of ethylenediaminetetraacetic acid occurs with the formation of trucated polypeptides.

DOI  10.1021/bi9524629,

Publication Year  1996

PubMed ID  8664281,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.