SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02698

Signal sequence   MIRFKKTKLIASIAMALCLFSQPVISFS

Length  28

Organism  Clostridium perfringens (strain 13 / Type A)

UniProt ID  P0C2E9,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1PFO,

Predicted Structure ID  SPKB02698.cif

Structure  SPKB02698.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3144.92894

Aliphatic index  118.5714286

Isoelectric point  11.08111025

Charge (pH=7)   3.935121171

Topological polar surface area  1124.43

Aromaticity  0.107142857

Average rotatable bonds  3.785714286

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  42

X logP energy  -6.53763

Hydropathy 



Literature Information


Title  Cold-labile hemolysin produced by limited proteolysis of theta-toxin from Clostridium perfringens.

DOI  10.1021/bi00368a032,

Publication Year  1986

PubMed ID  2878682,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.