General Information
SPKB ID SPKB02695
Signal sequence MKKTTLALSALALSLGLALSPLSATA
Length 26
Organism Escherichia coli (strain K12)
UniProt ID P0C0V0,
Motif 1..26
Activity Information
Pathway Sec
Natural/Artificial Natural
Subcellular location Cell membrane
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02695.cif
Physicochemical Information
Molecular weight 2543.10074
Aliphatic index 143.0769231
Isoelectric point 10.80537956
Charge (pH=7) 1.997394232
Topological polar surface area 975.68
Aromaticity 0
Average rotatable bonds 3.230769231
Number of hydrogen bond donors 35
Number of hydrogen bond acceptors 37
X logP energy -9.7332
Hydropathy 
Literature Information
Title The HtrA (DegP) protein, essential for Escherichia coli survival at high temperatures, is an endopeptidase.
DOI 10.1128/jb.172.4.1791-1797.1990,
Publication Year 1990
PubMed ID 2180903,
Patent ID NA,
