General Information
SPKB ID SPKB02693
Signal sequence MNKKKLGIRLLSLLALGGFVLANPVFA
Length 27
Organism Streptococcus pyogenes
UniProt ID P0C0J0,
Motif 1..27
Activity Information
Pathway Sec
Natural/Artificial Natural
Subcellular location Extracellular environment
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02693.cif
Physicochemical Information
Molecular weight 2884.60584
Aliphatic index 148.1481481
Isoelectric point 11.92450937
Charge (pH=7) 3.997095887
Topological polar surface area 1057.5
Aromaticity 0.074074074
Average rotatable bonds 3.62962963
Number of hydrogen bond donors 36
Number of hydrogen bond acceptors 36
X logP energy -5.22413
Hydropathy 
Literature Information
Title Nucleotide sequence of the streptococcal pyrogenic exotoxin type B gene and relationship between the toxin and the streptococcal proteinase precursor.
DOI 10.1128/jb.172.8.4536-4542.1990,
Publication Year 1990
PubMed ID 2198264,
Patent ID NA,
