SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02691

Signal sequence   MEKAKQVTWRLLAAGVCLLTVSSVARA

Length  27

Organism  Escherichia coli (strain K12)

UniProt ID  P0AGC3,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02691.cif

Structure  SPKB02691.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2902.50974

Aliphatic index  119.2592593

Isoelectric point  10.77794737

Charge (pH=7)   2.937188016

Topological polar surface area  1172.86

Aromaticity  0.037037037

Average rotatable bonds  3.592592593

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  40

X logP energy  -10.38966

Hydropathy 



Literature Information


Title  Murein-metabolizing enzymes from Escherichia coli: sequence analysis and controlled overexpression of the slt gene, which encodes the soluble lytic transglycosylase.

DOI  10.1128/jb.173.21.6773-6782.1991,

Publication Year  1991

PubMed ID  1938883,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.