General Information
SPKB ID SPKB02689
Signal sequence MFKSTLAAMAAVFALSALSPAAMA
Length 24
Organism Escherichia coli (strain K12)
UniProt ID P0AFL3,
Motif 1..24
Activity Information
Pathway Sec
Natural/Artificial Natural
Subcellular location Periplasmic space
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8XCK,
Predicted Structure ID SPKB02689.cif
Physicochemical Information
Molecular weight 2371.89674
Aliphatic index 98.33333333
Isoelectric point 9.700002532
Charge (pH=7) 0.997689266
Topological polar surface area 830.77
Aromaticity 0.083333333
Average rotatable bonds 3.083333333
Number of hydrogen bond donors 29
Number of hydrogen bond acceptors 33
X logP energy -6.7403
Hydropathy
Literature Information
Title Peptidyl-prolyl cis-trans-isomerase from Escherichia coli: a periplasmic homolog of cyclophilin that is not inhibited by cyclosporin A.
Publication Year 1990
PubMed ID 2190212,
Patent ID NA,