SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02688

Signal sequence   MPKFRVSLFSLALMLAVPFAPQAVA

Length  25

Organism  Escherichia coli (strain K12)

UniProt ID  P0AFI5,

Motif  1..25



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02688.cif

Structure  SPKB02688.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2705.35844

Aliphatic index  117.2

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  906.82

Aromaticity  0.12

Average rotatable bonds  3.28

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  33

X logP energy  -3.31933

Hydropathy 



Literature Information


Title  Identification and cloning of the gene encoding penicillin-binding protein 7 of Escherichia coli.

DOI  10.1128/jb.177.8.2074-2079.1995,

Publication Year  1995

PubMed ID  7721700,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.