SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02684

Signal sequence   MKKVLGVILGGLLLLPVVSNA

Length  21

Organism  Escherichia coli (strain K12)

UniProt ID  P0AES9,

Motif  1..21



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02684.cif

Structure  SPKB02684.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2134.73544

Aliphatic index  190

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  751.89

Aromaticity  0

Average rotatable bonds  3.428571429

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  27

X logP energy  -2.6599

Hydropathy 



Literature Information


Title  Function of the Escherichia coli nucleoid protein, H-NS: molecular analysis of a subset of proteins whose expression is enhanced in a hns deletion mutant.

DOI  10.1007/BF00282791,

Publication Year  1993

PubMed ID  8455549,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.