SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02683

Signal sequence   MKLAHLGRQALMGVMAVALVAGMSVKSFA

Length  29

Organism  Escherichia coli (strain K12)

UniProt ID  P0AEM9,

Motif  1..29



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02683.cif

Structure  SPKB02683.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2988.72264

Aliphatic index  114.4827586

Isoelectric point  11.82306209

Charge (pH=7)   3.088300011

Topological polar surface area  1104.29

Aromaticity  0.034482759

Average rotatable bonds  3.517241379

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  41

X logP energy  -8.21303

Hydropathy 



Literature Information


Title  Amino acid composition and N-terminal sequence of purified cystine binding protein of Escherichia coli.

DOI  10.1016/0024-3205(93)90103-a,

Publication Year  1993

PubMed ID  8450713,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.