General Information
SPKB ID SPKB02681
Signal sequence MKKIWLALAGLVLAFSASA
Length 19
Organism Escherichia coli (strain K12)
UniProt ID P0AEG4,
Motif 1..19
Activity Information
Pathway Sec
Natural/Artificial Natural
Subcellular location Periplasmic space
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8XFP,
Predicted Structure ID SPKB02681.cif
Physicochemical Information
Molecular weight 1990.47774
Aliphatic index 144.2105263
Isoelectric point 10.80537956
Charge (pH=7) 1.997394232
Topological polar surface area 695.41
Aromaticity 0.105263158
Average rotatable bonds 3.421052632
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 25
X logP energy -2.2955
Hydropathy 
Literature Information
Title The reactive and destabilizing disulfide bond of DsbA, a protein required for protein disulfide bond formation in vivo.
DOI 10.1021/bi00070a016,
Publication Year 1993
PubMed ID 8494885,
Patent ID NA,
