SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02679

Signal sequence   MNTIFSARIMKRLALTTALCTAFISAAHA

Length  29

Organism  Escherichia coli (strain K12)

UniProt ID  P0AEB2,

Motif  1..29



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6NTZ,

Predicted Structure ID  SPKB02679.cif

Structure  SPKB02679.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3124.77124

Aliphatic index  104.8275862

Isoelectric point  11.48120744

Charge (pH=7)   3.026617018

Topological polar surface area  1221.09

Aromaticity  0.068965517

Average rotatable bonds  3.517241379

Number of hydrogen bond donors  46

Number of hydrogen bond acceptors  44

X logP energy  -11.68546

Hydropathy 



Literature Information


Title  Amino acid sequence homologies between Escherichia coli penicillin-binding protein 5 and class A beta-lactamases.

DOI  10.1016/0014-5793(82)80840-5,

Publication Year  1982

PubMed ID  7042389,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.