SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02677

Signal sequence   MKFKTNKLSLNLVLASSLLAASIPAFA

Length  27

Organism  Escherichia coli (strain K12)

UniProt ID  P0ADV1,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02677.cif

Structure  SPKB02677.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2849.46794

Aliphatic index  130.3703704

Isoelectric point  11.10307074

Charge (pH=7)   2.997099198

Topological polar surface area  1076.52

Aromaticity  0.074074074

Average rotatable bonds  3.518518519

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  39

X logP energy  -8.6862

Hydropathy 



Literature Information


Title  Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.

DOI  10.1002/elps.1150180807,

Publication Year  1997

PubMed ID  9298646,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.