SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02673

Signal sequence   MKNWKTLLLGIAMIANTSFA

Length  20

Organism  Escherichia coli (strain K12)

UniProt ID  P0ABZ6,

Motif  1..20



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02673.cif

Structure  SPKB02673.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2223.71974

Aliphatic index  112.5

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  830.92

Aromaticity  0.1

Average rotatable bonds  3.7

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -5.2333

Hydropathy 



Literature Information


Title  SurA assists the folding of Escherichia coli outer membrane proteins.

DOI  10.1128/jb.178.6.1770-1773.1996,

Publication Year  1996

PubMed ID  8626309,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.