SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02667

Signal sequence   MRTLQGWLLPVFMLPMAVYA

Length  20

Organism  Escherichia coli (strain K12)

UniProt ID  P0A921,

Motif  1..20



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02667.cif

Structure  SPKB02667.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2337.92784

Aliphatic index  117

Isoelectric point  9.348807885

Charge (pH=7)   0.997130574

Topological polar surface area  759.88

Aromaticity  0.15

Average rotatable bonds  3.5

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  -0.12663

Hydropathy 



Literature Information


Title  The DNA sequence encoding pldA gene, the structural gene for detergent-resistant phospholipase A of E. coli.

DOI  10.1093/oxfordjournals.jbchem.a134997,

Publication Year  1984

PubMed ID  6397464,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.