SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02665

Signal sequence   MKQALRVAFGFLILWASVLHA

Length  21

Organism  Escherichia coli (strain K12)

UniProt ID  P0A855,

Motif  1..21



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1C5K,

Predicted Structure ID  SPKB02665.cif

Structure  SPKB02665.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2371.91514

Aliphatic index  139.5238095

Isoelectric point  11.65178972

Charge (pH=7)   2.088595045

Topological polar surface area  841.03

Aromaticity  0.142857143

Average rotatable bonds  3.619047619

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  28

X logP energy  -2.07383

Hydropathy 



Literature Information


Title  Maturation and localization of the TolB protein required for colicin import.

DOI  10.1128/jb.176.20.6392-6396.1994,

Publication Year  1994

PubMed ID  7929011,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.