SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02660

Signal sequence   MQGPWVLLLLGLRLQLSLG

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P09923,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02660.cif

Structure  SPKB02660.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2107.62834

Aliphatic index  179.4736842

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  762.43

Aromaticity  0.052631579

Average rotatable bonds  3.631578947

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  25

X logP energy  -2.18643

Hydropathy 



Literature Information


Title  Chemical nature of intestinal-type alkaline phosphatase in human kidney.

DOI  NA,

Publication Year  1992

PubMed ID  1458595,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.