General Information
SPKB ID SPKB02659
Signal sequence MWCIVLFSLLAWVYA
Length 15
Organism Homo sapiens (Human)
UniProt ID P09871,
Motif 1..15
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02659.cif
Physicochemical Information
Molecular weight 1815.26424
Aliphatic index 156
Isoelectric point 5.919503212
Charge (pH=7) -0.064840831
Topological polar surface area 542.76
Aromaticity 0.266666667
Average rotatable bonds 3.466666667
Number of hydrogen bond donors 21
Number of hydrogen bond acceptors 20
X logP energy 3.0359
Hydropathy
Literature Information
Title Human complement component C1s. Partial sequence determination of the heavy chain and identification of the peptide bond cleaved during activation.
DOI 10.1111/j.1432-1033.1986.tb09546.x,
Publication Year 1986
PubMed ID 3007145,
Patent ID NA,