SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02658

Signal sequence   MKVAIIFLLSALALLSLA

Length  18

Organism  Rattus norvegicus (Rat)

UniProt ID  P09655,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02658.cif

Structure  SPKB02658.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1887.43794

Aliphatic index  211.6666667

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  624.5

Aromaticity  0.055555556

Average rotatable bonds  3.5

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  23

X logP energy  -0.1463

Hydropathy 



Literature Information


Title  Purification, characterization and amino-acid sequencing of two pancreatic secretory trypsin inhibitors in rat pancreatic juice.

DOI  NA,

Publication Year  1988

PubMed ID  3202973,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.