SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02653

Signal sequence   MPKLNRCAIAIFTILSAISSPTLLA

Length  25

Organism  Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

UniProt ID  P09545,

Motif  1..25



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02653.cif

Structure  SPKB02653.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2645.25724

Aliphatic index  140.8

Isoelectric point  9.833242293

Charge (pH=7)   1.935711238

Topological polar surface area  976.3

Aromaticity  0.04

Average rotatable bonds  3.36

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  36

X logP energy  -7.57393

Hydropathy 



Literature Information


Title  Two-step processing for activation of the cytolysin/hemolysin of Vibrio cholerae O1 biotype El Tor: nucleotide sequence of the structural gene (hlyA) and characterization of the processed products.

DOI  10.1128/iai.58.12.4106-4116.1990,

Publication Year  1990

PubMed ID  2174833,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.