SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02652

Signal sequence   MISPFLLLAIGTCFASS

Length  17

Organism  Bos taurus (Bovine)

UniProt ID  P09487,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02652.cif

Structure  SPKB02652.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1771.16274

Aliphatic index  126.4705882

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  601.05

Aromaticity  0.117647059

Average rotatable bonds  3.176470588

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  24

X logP energy  -3.911

Hydropathy 



Literature Information


Title  Partial sequencing of human adult, human fetal, and bovine intestinal alkaline phosphatases: comparison with the human placental and liver isozymes.

DOI  10.1073/pnas.83.8.2368,

Publication Year  1986

PubMed ID  3458202,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.