SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02650

Signal sequence   MELCRVLLLIFSAAGPALCY

Length  20

Organism  Gallus gallus (Chicken)

UniProt ID  P09479,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02650.cif

Structure  SPKB02650.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2183.71324

Aliphatic index  146.5

Isoelectric point  6.133775205

Charge (pH=7)   -0.125043735

Topological polar surface area  747.09

Aromaticity  0.1

Average rotatable bonds  3.4

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -2.33653

Hydropathy 



Literature Information


Title  Brain and muscle nicotinic acetylcholine receptors are different but homologous proteins.

DOI  10.1073/pnas.82.15.5208,

Publication Year  1985

PubMed ID  3860855,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.