SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02648

Signal sequence   MLCLLLTLGVALVCGVPA

Length  18

Organism  Homo sapiens (Human)

UniProt ID  P09466,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02648.cif

Structure  SPKB02648.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1786.32284

Aliphatic index  189.4444444

Isoelectric point  5.826007312

Charge (pH=7)   -0.125965132

Topological polar surface area  569.46

Aromaticity  0

Average rotatable bonds  3.055555556

Number of hydrogen bond donors  21

Number of hydrogen bond acceptors  23

X logP energy  -1.3132

Hydropathy 



Literature Information


Title  Purification and characterization of an immunomodulatory endometrial protein, glycodelin.

DOI  10.1074/jbc.M010451200,

Publication Year  2001

PubMed ID  11278680,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.