General Information
SPKB ID SPKB02646
Signal sequence MARAALSAAPSNPRLLRVALLLLLLVAAGRRAAG
Length 34
Organism Homo sapiens (Human)
UniProt ID P09341,
Motif 1..34
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02646.cif
Physicochemical Information
Molecular weight 3454.23054
Aliphatic index 149.7058824
Isoelectric point 13.10207708
Charge (pH=7) 4.997967743
Topological polar surface area 1399.09
Aromaticity 0
Average rotatable bonds 3.294117647
Number of hydrogen bond donors 51
Number of hydrogen bond acceptors 44
X logP energy -12.47275
Hydropathy
Literature Information
Title Isolation of the CXC chemokines ENA-78, GRO alpha and GRO gamma from tumor cells and leukocytes reveals NH2-terminal heterogeneity. Functional comparison of different natural isoforms.
DOI 10.1046/j.1432-1327.1999.00166.x,
Publication Year 1999
PubMed ID 10095777,
Patent ID NA,