SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02645

Signal sequence   MRLTVLCAVCLLPGSLA

Length  17

Organism  Homo sapiens (Human)

UniProt ID  P09237,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02645.cif

Structure  SPKB02645.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1760.24464

Aliphatic index  160.5882353

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  622.49

Aromaticity  0

Average rotatable bonds  3.235294118

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  24

X logP energy  -3.87593

Hydropathy 



Literature Information


Title  Purification and characterization of extracellular matrix-degrading metalloproteinase, matrin (pump-1), secreted from human rectal carcinoma cell line.

DOI  NA,

Publication Year  1990

PubMed ID  2253219,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.