SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02641

Signal sequence   MAVVRVRAIVALLCLVAALGLA

Length  22

Organism  Gallus gallus (Chicken)

UniProt ID  P09102,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02641.cif

Structure  SPKB02641.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2222.86574

Aliphatic index  199.5454545

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  798.22

Aromaticity  0

Average rotatable bonds  3.272727273

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  27

X logP energy  -2.90406

Hydropathy 



Literature Information


Title  Molecular cloning of a multifunctional chicken protein acting as the prolyl 4-hydroxylase beta-subunit, protein disulphide-isomerase and a cellular thyroid-hormone-binding protein. Comparison of cDNA-deduced amino acid sequences with those in other species.

DOI  10.1042/bj2561005,

Publication Year  1988

PubMed ID  2851999,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.