General Information
SPKB ID SPKB02641
Signal sequence MAVVRVRAIVALLCLVAALGLA
Length 22
Organism Gallus gallus (Chicken)
UniProt ID P09102,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02641.cif
Physicochemical Information
Molecular weight 2222.86574
Aliphatic index 199.5454545
Isoelectric point 10.52640717
Charge (pH=7) 1.936002961
Topological polar surface area 798.22
Aromaticity 0
Average rotatable bonds 3.272727273
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 27
X logP energy -2.90406
Hydropathy
Literature Information
Title Molecular cloning of a multifunctional chicken protein acting as the prolyl 4-hydroxylase beta-subunit, protein disulphide-isomerase and a cellular thyroid-hormone-binding protein. Comparison of cDNA-deduced amino acid sequences with those in other species.
DOI 10.1042/bj2561005,
Publication Year 1988
PubMed ID 2851999,
Patent ID NA,