SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02640

Signal sequence   MKVLAAGIVPLLLLVLHWKHGAG

Length  23

Organism  Mus musculus (Mouse)

UniProt ID  P09056,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02640.cif

Structure  SPKB02640.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2437.07384

Aliphatic index  169.5652174

Isoelectric point  10.80546448

Charge (pH=7)   2.179212414

Topological polar surface area  819.92

Aromaticity  0.043478261

Average rotatable bonds  3.391304348

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -0.5186

Hydropathy 



Literature Information


Title  Genomic cloning and heterologous expression of human differentiation-stimulating factor.

DOI  10.1089/dna.1.1989.8.351,

Publication Year  1989

PubMed ID  2475312,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.