SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02639

Signal sequence   MRGRELPLVLLALVLCQAPRGPA

Length  23

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  P08989,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02639.cif

Structure  SPKB02639.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2474.06724

Aliphatic index  140

Isoelectric point  10.43741668

Charge (pH=7)   1.937774772

Topological polar surface area  943.24

Aromaticity  0

Average rotatable bonds  3.391304348

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  31

X logP energy  -5.90339

Hydropathy 



Literature Information


Title  Amino acid sequences of three bombesin-like peptides from canine intestine extracts.

DOI  NA,

Publication Year  1983

PubMed ID  6853532,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.