SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02637

Signal sequence   MGPHLLGRSSLLLLLLGMWWSVRPLCA

Length  27

Organism  Bos taurus (Bovine)

UniProt ID  P08904,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02637.cif

Structure  SPKB02637.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3020.75144

Aliphatic index  144.4444444

Isoelectric point  10.5273869

Charge (pH=7)   2.026912052

Topological polar surface area  1047.09

Aromaticity  0.074074074

Average rotatable bonds  3.481481481

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  37

X logP energy  -3.64626

Hydropathy 



Literature Information


Title  Primary structure of a non-secretory ribonuclease from bovine kidney.

DOI  10.1093/oxfordjournals.jbchem.a122460,

Publication Year  1988

PubMed ID  3182769,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.