SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02636

Signal sequence   MLAVGCALLAALLAAPGAA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P08887,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02636.cif

Structure  SPKB02636.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1697.12714

Aliphatic index  160

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  578.33

Aromaticity  0

Average rotatable bonds  2.684210526

Number of hydrogen bond donors  20

Number of hydrogen bond acceptors  22

X logP energy  -3.3777

Hydropathy 



Literature Information


Title  Soluble cytokine receptors are present in normal human urine.

DOI  10.1084/jem.170.4.1409,

Publication Year  1989

PubMed ID  2529343,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.