SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02628

Signal sequence   MRLAVVCFCLFGLASC

Length  16

Organism  Rattus norvegicus (Rat)

UniProt ID  P08721,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02628.cif

Structure  SPKB02628.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1733.19604

Aliphatic index  121.875

Isoelectric point  8.04679067

Charge (pH=7)   0.81205684

Topological polar surface area  581.95

Aromaticity  0.125

Average rotatable bonds  3.375

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  23

X logP energy  -2.92473

Hydropathy 



Literature Information


Title  Purification of a human milk protein closely similar to tumor-secreted phosphoproteins and osteopontin.

DOI  10.1016/0167-4838(89)90092-7,

Publication Year  1989

PubMed ID  2736258,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.