SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02626

Signal sequence   MGSRTPESPLHAVQLRWGPRRRPPLLPLLLLLLPPPPRVGG

Length  41

Organism  Homo sapiens (Human)

UniProt ID  P08648,

Motif  1..41



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  9B9J,

Predicted Structure ID  SPKB02626.cif

Structure  SPKB02626.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4542.50744

Aliphatic index  111.7073171

Isoelectric point  12.80105066

Charge (pH=7)   5.090648645

Topological polar surface area  1696.37

Aromaticity  0.024390244

Average rotatable bonds  3.243902439

Number of hydrogen bond donors  57

Number of hydrogen bond acceptors  55

X logP energy  -11.31098

Hydropathy 



Literature Information


Title  The very late antigen family of heterodimers is part of a superfamily of molecules involved in adhesion and embryogenesis.

DOI  10.1073/pnas.84.10.3239,

Publication Year  1987

PubMed ID  3033641,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.