SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02625

Signal sequence   MRLLAKIICLMLWAICVA

Length  18

Organism  Homo sapiens (Human)

UniProt ID  P08603,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02625.cif

Structure  SPKB02625.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2061.73764

Aliphatic index  184.4444444

Isoelectric point  8.828181491

Charge (pH=7)   1.873736522

Topological polar surface area  661.73

Aromaticity  0.055555556

Average rotatable bonds  3.777777778

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  25

X logP energy  1.16037

Hydropathy 



Literature Information


Title  Purification and structural studies on the complement-system control protein beta 1H (Factor H).

DOI  10.1042/bj2050285,

Publication Year  1982

PubMed ID  6215918,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.