SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02624

Signal sequence   MRKTYWLMALFAVL

Length  14

Organism  Thermus aquaticus

UniProt ID  P08594,

Motif  1..14



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02624.cif

Structure  SPKB02624.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1743.20134

Aliphatic index  118.5714286

Isoelectric point  10.45492462

Charge (pH=7)   1.99683554

Topological polar surface area  585.79

Aromaticity  0.214285714

Average rotatable bonds  3.928571429

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  21

X logP energy  0.72907

Hydropathy 



Literature Information


Title  Unique precursor structure of an extracellular protease, aqualysin I, with NH2- and COOH-terminal pro-sequences and its processing in Escherichia coli.

DOI  NA,

Publication Year  1990

PubMed ID  2182621,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.