General Information
SPKB ID SPKB02622
Signal sequence MARALCPLQALWLLEWVLLLLGPCAAPPAWA
Length 31
Organism Homo sapiens (Human)
UniProt ID P08514,
Motif 1..31
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6V4P,
Predicted Structure ID SPKB02622.cif
Physicochemical Information
Molecular weight 3388.19624
Aliphatic index 145.1612903
Isoelectric point 6.135737489
Charge (pH=7) -0.124193321
Topological polar surface area 1090.82
Aromaticity 0.096774194
Average rotatable bonds 3.129032258
Number of hydrogen bond donors 38
Number of hydrogen bond acceptors 38
X logP energy -0.01303
Hydropathy
Literature Information
Title Separation of important new platelet glycoproteins (GPIa, GPIc, GPIc*, GPIIa and GMP-140) by f.p.l.c. Characterization by monoclonal antibodies and gas-phase sequencing.
DOI 10.1042/bj2790419,
Publication Year 1991
PubMed ID 1953640,
Patent ID NA,