SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02621

Signal sequence   MTQYSSLLRGLAAGSAFLFLFAPTAFA

Length  27

Organism  Escherichia coli (strain K12)

UniProt ID  P08506,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02621.cif

Structure  SPKB02621.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2852.34354

Aliphatic index  94.44444444

Isoelectric point  9.348807885

Charge (pH=7)   0.997130574

Topological polar surface area  1037.5

Aromaticity  0.185185185

Average rotatable bonds  3.222222222

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  37

X logP energy  -7.93853

Hydropathy 



Literature Information


Title  Amino acid sequence homologies between Escherichia coli penicillin-binding protein 5 and class A beta-lactamases.

DOI  10.1016/0014-5793(82)80840-5,

Publication Year  1982

PubMed ID  7042389,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.