SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02620

Signal sequence   MKFLSARDFHPVAFLGLMLVTTTA

Length  24

Organism  Mus musculus (Mouse)

UniProt ID  P08505,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02620.cif

Structure  SPKB02620.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2667.22284

Aliphatic index  101.6666667

Isoelectric point  9.697024

Charge (pH=7)   1.089041529

Topological polar surface area  958.65

Aromaticity  0.125

Average rotatable bonds  3.5

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  35

X logP energy  -5.55583

Hydropathy 



Literature Information


Title  Purification and NH2-terminal amino acid sequence of a T-cell-derived lymphokine with growth factor activity for B-cell hybridomas.

DOI  10.1073/pnas.83.24.9679,

Publication Year  1986

PubMed ID  2948184,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.